Glutathione stabilizes ascorbic acid in aqueous solution
ثبت نشده
چکیده
This report shows that glutathione affects ascorbic acid degradation in aqueous solution resulting in a significant stabilization of the vitamin. For the GSH concentrations used in this work the effect was higher on diluted ascorbic acid solutions. It is also shown that for a fixed ascorbic acid concentration, as glutathione concentration increases the degradation reaction shifts from first to zero order.
منابع مشابه
Exploring the Protective Effect of Ascorbic Acid and Aqueous Extract of Spirulina platensis on Methotrexate-Induced Lipid Peroxidation
This study was designed to explore the protective effects of ascorbic acid and water extract of Spirulina platensis (blue green algae) on methotrexate-induced lipid peroxidation using goat liver as the lipid source. This in vitro evaluation was done by measuring the malondialdehyde, 4-hydroxy-2-nonenal, reduced glutathione and nitric oxide content of tissue homogenates....
متن کاملEffect of Aqueous Extract of Embelica officinalis on Selenite Induced Cataract in Rats
Cataract is clouding of the eye lens that reduces the amount of incoming light and results in deteriorating vision. Blindness is thought to reach 75 million by 2020. Of these, unoperated cataract may be expected to account for at least 35 million. Thus, the burden of cataract is increasing remorselessly. Embelica officinalis is reported to have a very good antioxidant property and thus we hypot...
متن کاملIrradiation of human insulin in aqueous solution, first step towards radiosterilization.
The degradation of irradiated human insulin in aqueous solutions was investigated in order to protect the protein against ionizing radiation. The influence of the drug concentration, excipients and irradiation temperature were studied. Aqueous solutions at pH 2 were irradiated by gamma rays or by accelerated electrons. Two different high-performance liquid chromatography (HPLC) methods were use...
متن کاملEffect of Aqueous Extract of Embelica officinalis on Selenite Induced Cataract in Rats
Cataract is clouding of the eye lens that reduces the amount of incoming light and results in deteriorating vision. Blindness is thought to reach 75 million by 2020. Of these, unoperated cataract may be expected to account for at least 35 million. Thus, the burden of cataract is increasing remorselessly. Embelica officinalis is reported to have a very good antioxidant property and thus we hypot...
متن کاملFactors affecting the concentration of ascorbic acid in the crystalline lens of cattle and rabbits.
It has been suggested that ascorbic acid is necessary for the transparency and metabolism of the crystalline lens (see Bellows, 1944). Primarily, this is based on well-authenticated observations of a loss of ascorbic acid from animal and human lenses undergoing spontaneous opacification. In experimentally induced cataract, however, loss of ascorbic acid does not always occur; thus, naphthalene ...
متن کامل